BDBM95473 3-(4-Nitrophenyl)-3,8-diazaspiro [5.6]dodecane-4,7,9-trione ::US20250388593, Example 225

SMILES O=C1CCCC2(CCN(c3ccc([N+](=O)[O-])cc3)C(=O)C2)C(=O)N1

InChI Key InChIKey=QIRXHAXMJXHBLM-UHFFFAOYSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 95473   

TargetProtein cereblon [318-426](Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 95473BDBM95473(3-(4-Nitrophenyl)-3,8-diazaspiro [5.6]dodecane-4,7...)
Affinity DataKd: >1.00E+5nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent