BDBM96978 (4-oxo-6-phenylthieno[2,3-d]pyrimidin-3(4H)-yl)acetonitrile::2-(4-keto-6-phenyl-thieno[2,3-d]pyrimidin-3-yl)acetonitrile::2-(4-oxidanylidene-6-phenyl-thieno[2,3-d]pyrimidin-3-yl)ethanenitrile::2-(4-oxo-6-phenyl-3-thieno[2,3-d]pyrimidinyl)acetonitrile::2-(4-oxo-6-phenylthieno[2,3-d]pyrimidin-3-yl)acetonitrile::MLS000662226::SMR000293136::cid_975007

SMILES O=C1CCC(N2Cc3c(ccc4c3OC[C@H]3CN(CC5CCN(c6ccc([C@@H]7c8ccc(O)cc8OC[C@@H]7c7ccccc7)cc6F)CC5)CCN43)C2=O)C(=O)N1

InChI Key InChIKey=RMYIOTOHVXSDJV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 96978   

TargetSteroid hormone receptor ERR1 LBD(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 96978BDBM96978(3-((R)-7-((1-(2-fluoro-4-((3S,4R)-7- hydroxy-3-phe...)
Affinity DataIC50: 5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 96978BDBM96978(3-((R)-7-((1-(2-fluoro-4-((3S,4R)-7- hydroxy-3-phe...)
Affinity DataIC50: 275nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent