BDBM97018 3-(6-(2-(2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2,7- diazaspiro[3.5 ]nonan-7-yl)acetyl)-1-oxo- 3,5,6,7-tetrahydropyrrolo[3,4-f]isoindol- 2(1H)-yl)piperidine-2,6-dione::US20260000676, Compound A48

SMILES O=C1CCC(N2Cc3cc4c(cc3C2=O)CN(C(=O)CN2CCC3(CC2)CN(c2ccc([C@H]5c6ccc(O)cc6OC[C@H]5c5ccccc5)cc2)C3)C4)C(=O)N1

InChI Key InChIKey=YIVSKZUSEWEYQU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97018   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97018BDBM97018(3-(6-(2-(2-(4-((3R,4S)-7-hydroxy-3- phenylchroman-...)
Affinity DataIC50: 275nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent