BDBM97057 3-(1'-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)piperidin-4- yl)methyl)-7-oxo-5,7-dihydro-2H,6H- spiro[furo[2,3-f]isoindole-3,4'-piperidin]- 6-yl)piperidine-2,6-dione::US20260000676, Compound A86

SMILES O=C1CCC(N2Cc3cc4c(cc3C2=O)OCC42CCN(CC3CCN(c4ccc([C@@H]5c6ccc(O)cc6OC[C@@H]5c5ccccc5)cc4)CC3)CC2)C(=O)N1

InChI Key InChIKey=UQHDAZNEGXGRDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97057   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97057BDBM97057(3-(1'-((1-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4...)
Affinity DataIC50: 275nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent