BDBM97112 (R)-3-((4-(1-((2-(4-((3S,4R)-7-hydroxy-3- phenylchroman-4-yl)phenyl)-2- azaspiro[3.5]nonan-7-yl)methyl)piperidin- 4-yl)phenyl)amino)piperidine-2,6-dione::US20260000676, Compound A141

SMILES O=C1CC[C@@H](Nc2ccc(C3CCN(CC4CCC5(CC4)CN(c4ccc([C@@H]6c7ccc(O)cc7OC[C@@H]6c6ccccc6)cc4)C5)CC3)cc2)C(=O)N1

InChI Key InChIKey=FXZDRKDLUPUSJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 97112   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
University Of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 97112BDBM97112((R)-3-((4-(1-((2-(4-((3S,4R)-7-hydroxy-3- phenylch...)
Affinity DataIC50: 275nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2026
Entry Details
US Patent