BDBM97376 Orexin receptor antagonist 16::US20130102619, 16

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1cc(Cl)ccc1-n1nccn1)Oc1cc(ccn1)C#N

InChI Key InChIKey=XNQHPHHSLRWILW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97376   

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandPNGBDBM97376(Orexin receptor antagonist 16 | US20130102619, 16)
Affinity DataKi:  57nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
TBA

US Patent
LigandPNGBDBM97376(Orexin receptor antagonist 16 | US20130102619, 16)
Affinity DataKi:  5.64E+3nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent