BDBM97392 Orexin receptor antagonist 24::US20130102619, 24

SMILES C[C@@H]1CC[C@H](CN1C(=O)c1ccc(OC(F)F)cc1-n1nccn1)Oc1cc(ccn1)C#N

InChI Key InChIKey=YUUYCGWLBCWGLU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97392   

TargetOrexin receptor type 2(Human)
TBA

US Patent
LigandPNGBDBM97392(Orexin receptor antagonist 24 | US20130102619, 24)
Affinity DataKi:  79nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
TBA

US Patent
LigandPNGBDBM97392(Orexin receptor antagonist 24 | US20130102619, 24)
Affinity DataKi:  2.39E+4nMAssay Description:The inhibition constant (Ki) is determined using a radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-14...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2013
Entry Details
US Patent