BDBM98019 US8486966, 15

SMILES C[C@H](Nc1nc2n(cnc2cc1F)-c1cc(C)[nH]n1)c1ncc(F)cn1

InChI Key InChIKey=PPFHEQNSISDCHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98019   

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent
LigandPNGBDBM98019(US8486966, 15)
Affinity DataIC50: 3.81E+3nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2013
Entry Details
US Patent