BDBM98892 US8497265, 218::US8497265, 241

SMILES N#CC1CCN(CC1)c1nccnc1OC1CN(C1)c1ccc2ccccc2n1

InChI Key InChIKey=WPJWGZGPTQYLIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 98892   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Amgen

US Patent
LigandPNGBDBM98892(US8497265, 218 | US8497265, 241)
Affinity DataIC50:  6.08nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM98892(US8497265, 218 | US8497265, 241)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human PDE10A using FAM-cAMP substrate by TR-FRET progressive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rattus norvegicus (rat))
Amgen

US Patent
LigandPNGBDBM98892(US8497265, 218 | US8497265, 241)
Affinity DataIC50:  60.8nMAssay Description:Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif). More data for this Ligand-Target Pair
In DepthDetails US Patent