BDBM99566 US8501936, 64

SMILES CN1CCN(CC1)c1ccc(Nc2nc3c(cccn3n2)-c2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=AJUSGEPLXKONFK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99566   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

US Patent
LigandChemical structure of BindingDB Monomer ID 99566BDBM99566(US8501936, 64)
Affinity DataIC50: 3.10nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Cephalon

US Patent
LigandChemical structure of BindingDB Monomer ID 99566BDBM99566(US8501936, 64)
Affinity DataIC50: 69.9nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetFocal adhesion kinase 1(Human)
Cephalon

US Patent
LigandChemical structure of BindingDB Monomer ID 99566BDBM99566(US8501936, 64)
Affinity DataIC50: 1.25E+3nMAssay Description:The ability of compounds to inhibit the kinase activity of baculovirus-expressed human FAK and JAK kinase using the time-resolved fluorescence (TRF) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent