BDBM99918 CHEMBL1945672::US8501991, 24

SMILES CN(C)CCCCC(=O)Nc1ccc(NC(=O)NC(=O)c2ccc(cc2)C(C)(C)C)cc1

InChI Key InChIKey=CECMKPFRICKMHJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99918   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

Curated by ChEMBL
LigandPNGBDBM99918(CHEMBL1945672 | US8501991, 24)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of recombinant human SitT1 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of St. Andrews

Curated by ChEMBL
LigandPNGBDBM99918(CHEMBL1945672 | US8501991, 24)
Affinity DataIC50: 2.90E+4nMAssay Description:SIRT1 inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2013
Entry Details
US Patent

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of St. Andrews

Curated by ChEMBL
LigandPNGBDBM99918(CHEMBL1945672 | US8501991, 24)
Affinity DataIC50: 8.84E+4nMAssay Description:Inhibition of recombinant human SitT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed