BDBM50459930 BMS-820836::Liafensine

SMILES [H][C@]1(CN(C)Cc2cc(ccc12)-c1ccc(N)nn1)c1ccc2ccccc2c1

InChI Key InChIKey=VCIBGDSRPUOBOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50459930   

TargetSodium-dependent serotonin transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50459930(BMS-820836 | Liafensine)
Affinity DataIC50: 1.10nMAssay Description:Binding affinity to SERT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50459930(BMS-820836 | Liafensine)
Affinity DataIC50: 5.70nMAssay Description:Binding affinity to DAT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Biocon Bristol-Myers Squibb R&D Centre

Curated by ChEMBL
LigandPNGBDBM50459930(BMS-820836 | Liafensine)
Affinity DataIC50: 8.80nMAssay Description:Binding affinity to NET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed