BDBM50173768 (biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphonic acid::BPH-306::CHEMBL196676

SMILES OC(c1cccc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=DUFXFUIMHWDTGA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50173768   

TargetDecaprenyl diphosphate synthase(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
University of California San Diego

LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50:  4.00E+4nMpH: 7.5Assay Description:We screened an in-house library of 53 compounds using trans-FPP as substrate. Briefly, the condensation of IPP and GPP, FPP, or cis-FPP catalyzed by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano De Investigaciones Cient£Ficas

Curated by ChEMBL
LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50:  810nMAssay Description:Inhibition of Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphotransferase(Trypanosoma cruzi)
Instituto Venezolano De Investigaciones Cient£Ficas

Curated by ChEMBL
LigandPNGBDBM50173768((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Affinity DataIC50:  3.47E+4nMAssay Description:Inhibitory activity against Trypanosoma cruzi hexokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed