BDBM50433422 BUDLEIN A

SMILES C=C1C(=O)O[C@@H]2/C=C(/CO)C3=CC(=O)[C@@](C)(C[C@@H](OC(=O)/C(C)=C/C)[C@@H]12)O3

InChI Key InChIKey=BMVJFNLJSZHNNS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50433422   

TargetTranscriptional activator Myb(Chicken)
University of M£Nster

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50433422BDBM50433422(BUDLEIN A)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of c-Myb-induced mim-1 gene expression in doxycyclin-treated chicken HD11 cells after 24 hrs by GFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetTranscriptional activator Myb(Chicken)
University of M£Nster

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50433422BDBM50433422(BUDLEIN A)
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of c-Myb-induced mim-1 gene expression in doxycyclin-treated chicken HD11 cells after 24 hrs by GFP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50433422BDBM50433422(BUDLEIN A)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (fumarate)(Leishmania major)
University of S£O Paulo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50433422BDBM50433422(BUDLEIN A)
Affinity DataIC50: 2.63E+5nMAssay Description:Inhibition of recombinant oligo-histidine-tagged Leishmania major DHODH expressed in Escherichia coli BL21(DE3) cells using DHO as substrate measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed