BDBM14479 CA-21::[amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-2-yl}amino)methylidene]azanium

SMILES [#7]\[#6](-[#7])=[#7+]/c1ccc(-[#7]-[#6](=O)-c2cc3ccccc3cc2-[#8])cn1

InChI Key InChIKey=AAOXQNKZMYOFJU-UHFFFAOYSA-N

Data  9 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 14479   

LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  100nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  200nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Celera

LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  870nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  1.10E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Celera

LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  9.60E+3nM ΔG°:  -6.77kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  5.40E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  7.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetPlasminogen(Human)
Celera

LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  1.30E+5nM ΔG°:  -5.24kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
LigandPNGBDBM14479([amino({5-[(3-hydroxynaphthalene-2-)amido]pyridin-...)
Affinity DataKi:  1.80E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed