BDBM14481 CA-23::[amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyridin-2-yl}amino)methylidene]azanium

SMILES [#7]\[#6](-[#7])=[#7+]/c1ccc(-[#7]-[#6](=O)-c2cc3ccccc3c(-[#8])c2-[#8])cn1

InChI Key InChIKey=PPMKDSOYTOUGBE-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 14481   

LigandPNGBDBM14481([amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyri...)
Affinity DataKi:  17nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
LigandPNGBDBM14481([amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyri...)
Affinity DataKi:  41nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
LigandPNGBDBM14481([amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyri...)
Affinity DataKi:  280nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetPlasminogen(Human)
Celera

LigandPNGBDBM14481([amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyri...)
Affinity DataKi:  4.00E+3nM ΔG°:  -7.28kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Celera

LigandPNGBDBM14481([amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyri...)
Affinity DataKi:  4.20E+4nM ΔG°:  -5.91kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14481([amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyri...)
Affinity DataKi:  8.00E+4nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

LigandPNGBDBM14481([amino({5-[(3,4-dihydroxynaphthalene-2-)amido]pyri...)
Affinity DataKi: >4.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMed