BDBM50009552 2-[6-Amino-2-(2-morpholin-4-yl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol::CHA::CHEMBL45891::N6-Cyclohexylado (CHA)
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC3CCCCC3)ncnc12
InChI Key InChIKey=SZBULDQSDUXAPJ-XNIJJKJLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 35 hits for monomerid = 50009552
Affinity DataKi: 0.850nMAssay Description:Inhibition of [3H]-CHA binding to rat brain membrane Adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Ability to displace the specific binding of [3H]CHA to adenosine A1 receptor from bovine brain cortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity for Adenosine A1 receptor in corpora striata of rats using [3H]NECAMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]-CHA or [3H]PIA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]CHA from adenosine A1 receptor of rat whole brainMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Affinity for Adenosine A1 receptor determined by [3H]N6-cyclohexyladenosine binding to rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to rat testesMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine in rat brainMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Binding of Adenosine A2 receptor in whole rat brain membrane using [3H]CHA as a RadioligandMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to bovine brainMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity for Adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHAMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Antagonist binding of N6-cyclohexyl-[3H]-adenosine to guinea pig brainMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Antagonist binding of L-N6-phenyl-isopropyl)-[3H]adenosine to rat fatMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Ability to displace the specific binding of [3H](R)-PIA to adenosine A3 receptor from rat testis membranesMore data for this Ligand-Target Pair
Affinity DataKi: 363nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 363nMAssay Description:Affinity for Adenosine A2 receptor determined by [3H]NECA binding to rat striatal membranesMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rat)
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Warner-Lambert/Parke-Davis Pharmaceutical Research
Curated by PDSP Ki Database
Affinity DataKi: 750nMAssay Description:Ability to displace the specific binding of [3H]-CGS- to adenosine A2A receptor form bovine brain striatal membranesMore data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nMAssay Description:Binding affinity for adenosine A2 receptor in corpora striata of rats using [3H]NECAMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Concentration required for 50% inhibition of [3H]-CHA binding on rat brain adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]CHA from rat brain adenosine receptorMore data for this Ligand-Target Pair
Affinity DataKd: 1.30nMAssay Description:Displacement of [3H] CGS 21680 from rat hippocampus adenosine A1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 790nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.850nMAssay Description:Evaluated for binding affinity against Adenosine A1 receptorChecked by AuthorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2b(Human)
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 5.26E+4nMAssay Description:Agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as stimulation of adenylate cyclaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [125I]ABA from adenosine A1 receptor of chick cerebellar membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 640nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Binding affinity towards the adenosine A1 receptor in cerebral cortices of Sprague-Dawley male rats using [3H]CHA as radioligand.More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair