BDBM36402 (3R)-3-Propyl-2,3-dihydrothieno[2,3-f][1,4]oxazepin-5-amine, 15::CID24894154

SMILES CCC[C@@H]1COc2ccsc2C(N)=N1

InChI Key InChIKey=JIIBOYBTIWHZFJ-SSDOTTSWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 36402   

TargetNitric oxide synthase, inducible(Human)
The Scripps Research Institute

LigandPNGBDBM36402((3R)-3-Propyl-2,3-dihydrothieno[2,3-f][1,4]oxazepi...)
Affinity DataIC50:  40nMpH: 7.0 T: 37°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Human)
The Scripps Research Institute

LigandPNGBDBM36402((3R)-3-Propyl-2,3-dihydrothieno[2,3-f][1,4]oxazepi...)
Affinity DataIC50:  50nMpH: 7.0 T: 37°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Human)
The Scripps Research Institute

LigandPNGBDBM36402((3R)-3-Propyl-2,3-dihydrothieno[2,3-f][1,4]oxazepi...)
Affinity DataIC50:  200nMpH: 7.0 T: 37°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed