BDBM50121650 3-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-3-carbonyl}-amino)-succinamic acid

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2CC1C(=O)N[C@@H](CC(O)=O)C(N)=O

InChI Key InChIKey=PVNQCTDTZFGLFA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50121650   

TargetDelta-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50121650(3-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...)
Affinity DataKi:  0.289nMAssay Description:Inhibition of [3H]DPDPE binding to Opioid receptor delta 1 of rat brain P2 synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50121650(3-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...)
Affinity DataKi:  2.57E+3nMAssay Description:Inhibition of [3H]DAGO binding to Opioid receptor mu 1 of rat brain P2 synaptosomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
University of Cagliari

Curated by ChEMBL
LigandPNGBDBM50121650(3-({2-[2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-p...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against electrically evoked contractions of guinea pig ileum (GPI)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed