BDBM50140917 6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-diazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4(9),5,7,12,14,16(22)-hexaene-2,13-diol

SMILES CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1cc(cnc41)-c1ccc(Cl)cc1)ccc5O

InChI Key InChIKey=YMQBQNZSHDBDTL-OOGIKFLQSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50140917   

TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140917(6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity at opioid receptor delta 1 by displacement of [3H]DADLE in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140917(6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-...)
Affinity DataKi:  17nMAssay Description:Apparent antagonist activity determined by measuring the ability to inhibit stimulation of [35S]GTP-gamma-S, binding to opioid receptor delta 1 in gu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140917(6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-...)
Affinity DataKi:  230nMAssay Description:Binding affinity at Opioid receptor mu 1 by displacement of [3H]DAMGO in rat brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140917(6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-...)
Affinity DataKi:  468nMAssay Description:Binding affinity at Opioid receptor kappa 1 by displacement of [3H]U-69593 in guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140917(6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-...)
Affinity DataKi:  767nMAssay Description:Apparent binding affinity of compound was determined by antagonism towards Opioid receptor kappa 1 in [35S]GTP-gamma-S, binding assay in guinea pig c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50140917(6-(4-chlorophenyl)-19-methyl-(2S,10R)-11-oxa-8,19-...)
Affinity DataKi: >1.00E+3nMAssay Description:Apparent binding affinity of compound was determined by antagonism towards Opioid receptor mu 1 in [35S]GTP-gamma-S, binding assay in guinea pig caud...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed