BDBM50242184 Scalaradial
SMILES [H][C@@]12CC[C@@]3(C)[C@]4([H])CC=C(C=O)[C@H](C=O)[C@@]4(C)[C@H](C[C@]3([H])[C@@]1(C)CCCC2(C)C)OC(C)=O
InChI Key InChIKey=ADWFEADZGIHPDE-QGERINELSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50242184
Affinity DataIC50: 15nMAssay Description:In vitro inhibitory activity against human synovial fluid phospholipase A2 (HSF-PLA2) by monitoring hydrolysis of [3H]-arachidonic acid labeled E. co...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 2(Rat)
Queen'S Center For Biomedical Research
Curated by ChEMBL
Queen'S Center For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of TRPM2 in rat INS-1 cells assessed as reduction in ADPR-induced intracellular calcium flux measured after 60 mins by whole cell patch cl...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 2(Human)
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 2(Human)
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human FLAG-tagged TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced intracellular calcium flux after 30 to 60 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of bee venom PLA2More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 7(Mouse)
Queen'S Center For Biomedical Research
Curated by ChEMBL
Queen'S Center For Biomedical Research
Curated by ChEMBL
Affinity DataIC50: 760nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair