BDBM50098674 (E)-17-(2-butenyl)-6,7-dehydro-4,5alpha-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinan

SMILES C\C=C\CN1CC[C@@]23[C@H]4Oc5c2c(CC1[C@]3(O)Cc1c4[nH]c2ccccc12)ccc5O

InChI Key InChIKey=PUQMBDFIIVFHRS-OAXKHTBJSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50098674   

TargetDelta-type opioid receptor(MOUSE)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098674((E)-17-(2-butenyl)-6,7-dehydro-4,5alpha-epoxy-3,14...)
Affinity DataKi:  0.680nMAssay Description:Antagonist activity of compound on agonist stimulated [35S]GTP-gamma-S binding on delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098674((E)-17-(2-butenyl)-6,7-dehydro-4,5alpha-epoxy-3,14...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H]DADLE at delta-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098674((E)-17-(2-butenyl)-6,7-dehydro-4,5alpha-epoxy-3,14...)
Affinity DataKi:  30nMAssay Description:Antagonist activity of compound on agonist stimulated [35S]GTP-gamma-S binding on mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098674((E)-17-(2-butenyl)-6,7-dehydro-4,5alpha-epoxy-3,14...)
Affinity DataKi:  118nMAssay Description:Antagonist activity of compound on U50,488H stimulated [35S]GTP-gamma-S binding to opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098674((E)-17-(2-butenyl)-6,7-dehydro-4,5alpha-epoxy-3,14...)
Affinity DataKi:  960nMAssay Description:Displacement of [3H]U-69593 at opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50098674((E)-17-(2-butenyl)-6,7-dehydro-4,5alpha-epoxy-3,14...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]DAMGO at mu-opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed