BDBM50005258 CHEMBL18762::D-367::[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-propyl-amine::[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-propyl-amine(N-n-Pr-DOB)

SMILES CCCNC(C)Cc1cc(OC)c(Br)cc1OC

InChI Key InChIKey=UGQKMZIPUUQGHA-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50005258   

Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  89nMAssay Description:Displacement of [125I]DOI from recombinant human 5HT2A expressed in Syrian hamster AV12 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  514nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  521nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  976nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  1.32E+3nMAssay Description:Binding affinity for 5-hydroxytryptamine 1 receptor of rat prefrontal cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2018
Entry Details Article
PubMed
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  1.32E+3nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  1.93E+3nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  1.93E+3nMAssay Description:Displacement of [3H]ketanserin from rat prefrontal cortex 5-hydroxytryptamine 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2018
Entry Details Article
PubMed
TargetSerotonin 2 (5-HT2) receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi:  2.46E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using [3H]ketanserin as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50005258(CHEMBL18762 | [2-(4-Bromo-2,5-dimethoxy-phenyl)-1-...)
Affinity DataKi: >1.00E+4nMAssay Description:Compound was tested for binding affinity towards 5-HT1C (5-HT1C) receptor from frontal cortical regions of male Sprague-Dawley rat homogenates, using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2012
Entry Details Article
PubMed