BDBM298298 DC403113::N-((S)-l-(((S)-4-(benzylamino)-3,4-dione-1- ((S)-2-oxopiperidin-3-yl)but-2-yl)amino)-3- cyclohexyl-1-oxopropan-2-yl)-benzofuran-2- carboxamide::US12636275, Compound A13

SMILES O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1cc2ccccc2o1

InChI Key InChIKey=SPWWDAZUHUGPIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298298   

TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298298BDBM298298(DC403113 | N-((S)-l-(((S)-4-(benzylamino)-3,4-dion...)
Affinity DataIC50: 1.36nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298298BDBM298298(DC403113 | N-((S)-l-(((S)-4-(benzylamino)-3,4-dion...)
Affinity DataIC50: 2.40E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent