BDBM298310 DC404001::N-((S)-1-(((S)-4-(benzylamino)-3,4-dione-1- ((S)-2-oxopyrrolidin-3-yl)but-2-yl)amino)-3- cyclohexyl-1-oxopropan-2-yl)-quinoline-2- carboxamide::US12636275, Compound A42

SMILES O=C(NCc1ccccc1)C(=O)[C@H](C[C@@H]1CCNC1=O)NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccc2ccccc2n1

InChI Key InChIKey=WNRZJUPEKVSVGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 298310   

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298310BDBM298310(DC404001 | N-((S)-1-(((S)-4-(benzylamino)-3,4-dion...)
Affinity DataIC50: 3.00E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent