BDBM50633395 DANIRIXIN::Danirixin::Danirixina::Danirixine::GSK-1325756B::GSK1325756::GSK1325756B::Gsk1325756

SMILES Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(c1O)S(=O)(=O)[C@H]1CCCNC1

InChI Key InChIKey=NGYNBSHYFOFVLS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50633395   

TargetC-X-C chemokine receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633395BDBM50633395(Danirixin | Danirixine | Danirixina | Gsk1325756 |...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity to CXCR2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-X-C chemokine receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633395BDBM50633395(Danirixin | Danirixine | Danirixina | Gsk1325756 |...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at CXCR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetC-X-C chemokine receptor type 2(Human)
University of Bonn

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50633395BDBM50633395(Danirixin | Danirixine | Danirixina | Gsk1325756 |...)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CXCL8 from human CXCR2 transfected in CHO-K1 cell membrane incubated for 45 mins by scintillation proximity binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed