BDBM28782 (3E)-3-(methoxyimino)-2-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}methyl)pentanoic acid::E/Z=3/1::alpha-acyl-beta-phenylpropanoic acid deriv., 11g

SMILES N#Cc1ccc(-c2ccc(C[C@H](NC(=O)c3c(F)cc(N[C@H](c4ccccc4)C(F)(F)F)cc3F)C(=O)O)c3cccnc23)c(Cl)c1

InChI Key InChIKey=XYTJOTIBVYKENU-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28782   

TargetIntegrin alpha-4/beta-7(Human)
GILEAD SCIENCES, INC.

US Patent
LigandChemical structure of BindingDB Monomer ID 28782BDBM28782(US11116760, Example 86)
Affinity DataEC50:  8.30nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2026
Entry Details US Patent