BDBM50597697 ALKANNIN::CHEBI:2578::E103

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6@H](-[#8])-[#6]-1=[#6]-[#6](=O)-c2c(-[#8])ccc(-[#8])c2-[#6]-1=O

InChI Key InChIKey=NJFLJGLXDJGZQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50597697   

TargetCOP9 signalosome complex subunit 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50597697(CHEBI:2578 | E103 | ALKANNIN)
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminal His6-tagged CSN5 (2 to 257 residues) (unknown origin) transfected in Transetta cells preincubated for 20 mins followed by N-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50597697(CHEBI:2578 | E103 | ALKANNIN)
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal His6-tagged CSN5 (2 to 257 residues) (unknown origin) transfected in Transetta cells preincubated for 20 mins followed by N-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50597697(CHEBI:2578 | E103 | ALKANNIN)
Affinity DataIC50: 900nMAssay Description:Inhibition of PKM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetPyruvate kinase PKM(Human)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50597697(CHEBI:2578 | E103 | ALKANNIN)
Affinity DataIC50: 900nMAssay Description:Inhibition of PKM2 (unknown origin) Hie78, Lys207, Asn75, Ile51, Ser362, Ser205, Gly128 residuesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed