BDBM50587053 E133

SMILES CCOc1ccc(Nc2ccc(cc2)C(=C2\C=C/C(/C=C2C)=[N+](/CC)Cc2cccc(c2)S([O-])(=O)=O)\c2ccc(cc2C)N(CC)Cc2cccc(c2)S(O)(=O)=O)cc1

InChI Key InChIKey=YVNQAIFQFWTPLQ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50587053   

TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50587053(E133)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-A-804598 from rat P2X7 receptor expressed in HEK293 cell membrane by in vitro binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Mus musculus)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50587053(E133)
Affinity DataIC50:  1.30E+3nMAssay Description:Antagonist activity at mouse P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium-flux measured after 60 mins by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50587053(E133)
Affinity DataIC50:  5.80E+3nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium-flux measured after 60 mins by F...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Rattus norvegicus (Rat))
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50587053(E133)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at rat P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced calcium-flux measured after 60 mins by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed