BDBM50001862 (N-(o-methoxyphenyl)piperazine)1-(2-Methoxy-phenyl)-piperazine::1-(2-Methoxy-phenyl)-piperazine::2-METHOXYPHENYLPIPERAZINE::4-(2-Methoxy-phenyl)-piperazin-1-ium::CHEMBL9666::EN300-33366
SMILES COc1ccccc1N1CCNCC1
InChI Key InChIKey=VNZLQLYBRIOLFZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 39 hits for monomerid = 50001862
Affinity DataKi: 1.20nMAssay Description:Binding affinity against 5 Hydroxy tryptamine 6 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor by displacing [3H]WB-4101 from rat hippocampusMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 9.5nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 1A receptor by [3H]-WB-4101 displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 12.9nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Binding affinity of a compound to rat brain 5-hydroxytryptamine 1A (serotonin) receptor assayed by radiolabeled [3H]-8-OH-DPAT ligand displacementMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1B(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 1B receptor by [3H]-5-HT displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 28nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 1 receptor by displacing [3H]5-HT radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1F(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 29nMAssay Description:Inhibition of [3H]5-HT radioligand binding against 5-hydroxytryptamine 1 receptorMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Evaluated for binding affinity towards 5-hydroxytryptamine 1A receptor in rat brainMore data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >100nMAssay Description:The compound was tested for its binding affinity towards 5-hydroxytryptamine 2 receptor by displacing [3H]ketanserin radioligand in rat cerebral cort...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
Affinity DataKi: 126nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenateMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Displacement of [3H]-2-(di-N-propylamino)-8-hydroxytetralin from central 5-hydroxytryptamine 1A receptor recognition sites in rat frontal cortex homo...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 7(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
Affinity DataKi: 243nMAssay Description:Displacement of [3H]LSD from rat rat kidney proximal convoluted tubule 5HT7R expressed in COS7 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 281nMAssay Description:Binding affinity for 5-hydroxytryptamine 1A receptor measured by displacing [3H]-8-OH-DPAT from rat cortical membranesMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Rat)
Virginia Commonwealth University
Curated by PDSP Ki Database
Virginia Commonwealth University
Curated by PDSP Ki Database
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:The compound was tested for its binding affinity towards Alpha-1 adrenergic receptor by displacing [3H]WB-4101 radioligand in rat cerebral cortexMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Binding affinity against rat Alpha-1 adrenergic receptor.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 680nMAssay Description:Displacement of [125I]IABN from human D2L receptor expressed in HEK293 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against rat Dopamine receptor D2.More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at rat Dopamine receptor D1 by [3H]-SCH-23,390 displacement.More data for this Ligand-Target Pair
TargetSerotonin 2 (5-HT2) receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 2 receptor by [3H]ketanserin displacement.More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity towards dopamine receptor D2 by displacing [3H]spiperone radioligand in rat striatumMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Rat)
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Mcneil Pharmaceutical and Janssen Research Foundation Worldwide
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:In vitro displacement of [3H]-spiperone from Dopamine receptor D2 binding site in rat striatum.More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 2.26E+3nMAssay Description:Displacement of [125I]IABN from human D3 receptor expressed in HEK293 cells after 60 mins by gamma counting analysisMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A/3B/3C/3D/3E(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Compound was tested for the inhibition of [3H]-GR-65,630 binding to 5-hydroxytryptamine 3 receptor expressed in NG 108-15 cellsMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 6(Rat)
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
National Institute of Neurological Disorders and Stroke
Curated by PDSP Ki Database
TargetSerotonin 2 (5-HT2) receptor(Rat)
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
R. W. Johnson Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 3.50E+3nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor of rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 3.51E+3nMAssay Description:Binding affinity measured for alpha-1 adrenergic receptor by displacement of [3H]-prazosin from rat cortical membranesMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataKi: 4.11E+3nMAssay Description:Displacement of [3H]spiperone from human D2L receptor expressed in FlpIn CHO cell membrane after 3 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Human)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 1.12E+4nMAssay Description:Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine ventricular...More data for this Ligand-Target Pair
Affinity DataIC50: 2.98E+3nMAssay Description:IC50 values were determined for the whole plate in case of Chan-Lam coupling, using 5 point 3-fold dilutions (starting from 10 μM).More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
National Institute On Drug Abuse-Intramural Research Program
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Antagonist activity at human D2L receptor expressed in FlpIn CHO cells assessed as inhibition of dopamine-induced ERK1/2 phosphorylation treated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+4nMAssay Description:Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine lung ti...More data for this Ligand-Target Pair