BDBM50370717 EPOXOMYCIN::Epoxomicin

SMILES CCC(C)C(NC(=O)C(C(C)CC)N(C)C(C)=O)C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)C1(C)CO1

InChI Key InChIKey=DOGIDQKFVLKMLQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50370717   

TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50370717(Epoxomicin | EPOXOMYCIN)
Affinity DataIC50: 26nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50370717(Epoxomicin | EPOXOMYCIN)
Affinity DataIC50: 47nMAssay Description:Inhibition of chymotrypsin like activity of proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50370717(Epoxomicin | EPOXOMYCIN)
Affinity DataIC50: 300nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50370717(Epoxomicin | EPOXOMYCIN)
Affinity DataIC50: 980nMAssay Description:Inhibition of trypsin like activity of proteasomeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed