BDBM50598657 CHEMBL600353::GNF-Pf-1339

SMILES CCCCCC[n+]1ccccc1C=Cc1ccc(cc1)N(C)C

InChI Key InChIKey=OQPXCZGFVBKXJK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50598657   

TargetLysine-specific demethylase 4A(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50598657(GNF-Pf-1339 | CHEMBL600353)
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM4A in human MIA PaCa-2 cells assessed as induction of H3K9me3 measured by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 2A(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50598657(GNF-Pf-1339 | CHEMBL600353)
Affinity DataIC50: 280nMAssay Description:Inhibition of KDM2A in human MIA PaCa-2 cells assessed as induction of H3K36me2 measured by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50598657(GNF-Pf-1339 | CHEMBL600353)
Affinity DataKi:  420nMAssay Description:Inhibition of His6-tagged recombinant human KDM4A (1 to 359 residues) measured by fluorescence polarization based competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed