BDBM50430488 CHEMBL531383::GNF-Pf-2144

SMILES CCSC1=CC(=O)c2ccccc2C1=O

InChI Key InChIKey=JTIVMHQHPSUHGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430488   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shibaura Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50430488(GNF-Pf-2144 | CHEMBL531383)
Affinity DataIC50: 5.35E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using Dabcyl-KTSAVLQSGFRKME-Edans as a substrate preincubated for 30 mins followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetSterol O-acyltransferase 1(Human)
Dongguk University-Seoul

Curated by ChEMBL
LigandPNGBDBM50430488(GNF-Pf-2144 | CHEMBL531383)
Affinity DataIC50: 7.51E+3nMAssay Description:Inhibition of human macrophage ACAT expressed in human HepG2 cells using [14C]oleoyl-CoA as substrate incubated for 20 mins prior to substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed