BDBM50238736 CHEMBL1091535::GW7604

SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(O)=O)cc1)c1ccccc1

InChI Key InChIKey=SCVIEONTACSLJA-YGCRUXFTSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50238736   

TargetEstrogen receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]estradiol from full-length human ERalpha receptor by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataIC50:  6.80nMAssay Description:Displacement of fluorescein-labeled estradiol (fluoromone) from human recombinant full-length estrogen receptor beta after 2 hrs by fluorescence pola...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataIC50:  5.40nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataIC50:  238nMAssay Description:Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataIC50:  154nMAssay Description:Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataIC50:  4.40nMAssay Description:Displacement of fluorescein-labeled estradiol (fluoromone) from human recombinant full-length estrogen receptor alpha after 2 hrs by fluorescence pol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50238736(CHEMBL1091535 | GW7604)
Affinity DataIC50:  3.80nMAssay Description:Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed