BDBM50078263 1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-phenyl)-ethyl]-thiourea::CHEMBL295585::HI-240

SMILES Fc1ccccc1CCNC(=S)Nc1ccc(Br)cn1

InChI Key InChIKey=MIJLSRZJDIBHJU-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50078263   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(HI-240 | 1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-p...)
Affinity DataIC50: 600nMAssay Description:Inhibition of purified recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(HI-240 | 1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-p...)
Affinity DataKi:  600nMAssay Description:Binding affinity against HIV reverse transcriptase (Estimated Ki)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(HI-240 | 1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-p...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(HI-240 | 1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-p...)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant reverse transcriptase (RT) in cell-free Quan-T-RT assay systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Institute

Curated by ChEMBL
LigandPNGBDBM50078263(HI-240 | 1-(5-Bromo-pyridin-2-yl)-3-[2-(2-fluoro-p...)
Affinity DataIC50: 600nMAssay Description:Compound was evaluated for its inhibitory activity against recombinant HIV-1 Reverse transcriptase using cell free RT inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2012
Entry Details Article
PubMed