BDBM50594953 CHEBI:18418::Dl-demethylcoclaurine::HIGENAMINE::Higenamine

SMILES Oc1ccc(CC2NCCc3cc(O)c(O)cc23)cc1

InChI Key InChIKey=WZRCQWQRFZITDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50594953   

TargetLysine-specific histone demethylase 1A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594953(HIGENAMINE | CHEBI:18418 | Dl-demethylcoclaurine |...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of full-length recombinant KDM1A (unknown origin) expressed in Escherichia coli BL21 DE using H3K4Me2 peptide as substrate incubated for 0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594953(HIGENAMINE | CHEBI:18418 | Dl-demethylcoclaurine |...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of recombinant full-length LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) cells using H3K4me2 peptide as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50594953(HIGENAMINE | CHEBI:18418 | Dl-demethylcoclaurine |...)
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed