BDBM50492435 HWA-285::Propentofylline

SMILES CCCn1cnc2c1C(=O)N(C(=O)N2C)CCCCC(=O)C

InChI Key InChIKey=RBQOQRRFDPXAGN-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492435   

TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50492435(HWA-285 | Propentofylline)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50492435(HWA-285 | Propentofylline)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed