BDBM50287796 CHEMBL308150::ICI-215001::{4-[2-((S)-2-Hydroxy-3-phenoxy-propylamino)-ethoxy]-phenoxy}-acetic acid

SMILES O[C@@H](CNCCOc1ccc(OCC(O)=O)cc1)COc1ccccc1

InChI Key InChIKey=MXWICZOXPUWAHY-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287796   

TargetBeta-1 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287796({4-[2-((S)-2-Hydroxy-3-phenoxy-propylamino)-ethoxy...)
Affinity DataKi:  300nMAssay Description:Compound was tested for its binding affinity against Beta-1 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287796({4-[2-((S)-2-Hydroxy-3-phenoxy-propylamino)-ethoxy...)
Affinity DataKi:  520nMAssay Description:Compound was tested for its binding affinity against beta3 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-3 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287796({4-[2-((S)-2-Hydroxy-3-phenoxy-propylamino)-ethoxy...)
Affinity DataEC50:  550nMAssay Description:Compound was tested for its ability to stimulate adenylyl cyclase activity in CHO-beta-3 adrenergic receptor cell membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetBeta-2 adrenergic receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287796({4-[2-((S)-2-Hydroxy-3-phenoxy-propylamino)-ethoxy...)
Affinity DataKi:  2.35E+3nMAssay Description:Compound was tested for its binding affinity against beta2 adrenergic receptor in CHO cell membrane using [125I]iodocyanopindolol as the radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article