BDBM106782 7‐hydroxy‐3‐(4‐nitrophenyl)‐4H‐chromen‐4‐one::7-Hydroxy-4′-nitro-isoflavone (3c)::IR-406

SMILES Oc1ccc2c(c1)occ(-c1ccc(cc1)[N+]([O-])=O)c2=O

InChI Key InChIKey=CEESSYSSRMOMDE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 106782   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad De Santiago De Chile

LigandPNGBDBM106782(7‐hydroxy‐3‐(4‐nitrophenyl...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad De Santiago

LigandPNGBDBM106782(7‐hydroxy‐3‐(4‐nitrophenyl...)
Affinity DataIC50:  5.00E+3nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad De Santiago De Chile

LigandPNGBDBM106782(7‐hydroxy‐3‐(4‐nitrophenyl...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:All reactions were carried in a volume of 2 mL stirred at 23°C with approximately 2.040 Units of 12-hLOX, 4.200 Units of 15-hLOX-1, and 6.600 Un...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed