BDBM50150854 6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-oxoethylamino)ethylamino)nicotinonitrile::6-{2-[2-(5-Cyano-4,5-dihydro-pyrazol-1-yl)-2-oxo-ethylamino]-ethylamino}-nicotinonitrile::CHEMBL184651::KR-62436

SMILES O=C(CNCCNc1ccc(cn1)C#N)N1N=CCC1C#N

InChI Key InChIKey=XNYVGGJJENHRBZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50150854   

TargetDipeptidyl peptidase 4(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50: 410nMAssay Description:Inhibitory concentration against dipeptidyl peptidase IV in Caco-2 cell assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50: 490nMAssay Description:Inhibition of pig kidney DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Rat)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50: 780nMAssay Description:Inhibition of DPP4 in rat plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Rat)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against rat dipeptidyl peptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Pig)
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50150854(6-(2-(2-(5-cyano-4,5-dihydro-1H-pyrazol-1-yl)-2-ox...)
Affinity DataIC50: 960nMAssay Description:Inhibitory concentration against dipeptidyl peptidase IV of porcine kidneyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed