BDBM50050463 2-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-3H-imidazo[4,5-b]pyridine::3-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-1H-pyrrolo[2,3-b]pyridine::3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine::3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-pyrrolo[2,3-b]pyridine (L-745870)::4-(4-Chloro-phenyl)-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-piperazin-1-ium::CHEMBL267014::L-745870

SMILES Clc4ccc(N3CCN(Cc1c[nH]c2ncccc12)CC3)cc4

InChI Key InChIKey=OGJGQVFWEPNYSB-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50050463   

TargetD(4) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050463BDBM50050463(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi:  2.80nMAssay Description:Displacement of 3H-N-Methylspiperone from DRD4 in human HEK293T cells membrane assessed as inhibition constant incubated for 2 hrs by radioligand com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50050463BDBM50050463(3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-py...)
Affinity DataKi:  9.11E+3nMAssay Description:Displacement of 3H-N-Methylspiperone from DRD2 in human HEK293T cells membrane assessed as inhibition constant incubated for 2 hrs by radioligand com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed