BDBM50063907 (S)-4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-2-tert-butylcarbamoyl-piperazine-1-carboxylic acid benzyl ester::CHEMBL19476::L-765314
SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN([C@@H](C1)C(=O)NC(C)(C)C)C(=O)OCc1ccccc1
InChI Key InChIKey=CGWOIDCAGBKOQL-FQEVSTJZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50063907
Affinity DataKi: 2nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1B adren...More data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1D adren...More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Compound was tested for its binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adren...More data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Binding constant measured against Alpha-1A adrenergic receptor in human prostate; +:inactiveMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 590nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the human prostate Alpha-1A adrenergic receptor subtypeMore data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 5.80E+3nMAssay Description:Compound was tested for the tissue binding affinity using [125I]- HEAT as radioligand to the human aorta Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat spleen Alpha-1B adrenergic receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat prostate Alpha-1A adrenergic receptor subtype.More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:Compound was tested for the tissue binding affinity using [3H]- Prazosin as radioligand to the rat liver Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair