BDBM50168962 (3S,4aR,6S,8aR)-6-(4-Carboxy-benzyl)-decahydro-isoquinoline-3-carboxylic acid::6-(4-Carboxy-benzyl)-decahydro-isoquinoline-3-carboxylic acid::CHEMBL274226::LY 382884

SMILES OC(=O)[C@@H]1C[C@H]2C[C@@H](Cc3ccc(cc3)C(O)=O)CC[C@H]2CN1

InChI Key InChIKey=YVMADKYPKNLVGU-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50168962   

TargetGlutamate receptor ionotropic, kainate 1(Human)
Centro De Investigaci�N Lilly

Curated by ChEMBL
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of [3H]ATPA from human Gluk1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
Centro De Investigaci�N Lilly

Curated by ChEMBL
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi:  3.60E+3nMAssay Description:Binding affinity to GluK1 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi:  4.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetGlutamate receptor 4(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2012
Entry Details Article
PubMed
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2012
Entry Details Article
PubMed
TargetGlutamate receptor 1(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/10/2012
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
Centro De Investigaci�N Lilly

Curated by ChEMBL
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi:  1.71E+4nMAssay Description:Inhibition of [3H]-KA binding to iontropic glutamate receptor 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]KA binding to iontropic glutamate receptor 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of [3H]-AMPA binding to human GluR2 receptors expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi:  5.53E+5nMAssay Description:Binding affinity to GluA2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetGlutamate receptor 2(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM50168962(LY 382884 | CHEMBL274226 | 6-(4-Carboxy-benzyl)-de...)
Affinity DataKi:  5.53E+5nMAssay Description:Displacement of [3H]AMPA from homomeric recombinant GluA2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed