BDBM50204451 CHEMBL397035::MCL-429
SMILES O=C(Nc1ccccc1)Oc1ccc2CC3C4CCCCC4(CCN3CC3CC3)c2c1
InChI Key InChIKey=PNQVNINMHSUQSR-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50204451
Affinity DataKi: 0.0460nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptors expressed in CHO cell membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cells assessed as DAMGO-stimulated [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.440nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as maximal stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 0.380nMAssay Description:Agonist activity at huma kappa opioid receptor expressed in CHO cells assessed as U50488-stimulated of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair