BDBM50194275 CHEMBL384915::H-Dmt-Tic-beta-Ala-OH::MCL-451

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N1Cc2ccccc2C[C@H]1C(=O)NCCC(O)=O

InChI Key InChIKey=FEJBKZCTAXWTTN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50194275   

TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50194275(MCL-451 | H-Dmt-Tic-beta-Ala-OH | CHEMBL384915)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50194275(MCL-451 | H-Dmt-Tic-beta-Ala-OH | CHEMBL384915)
Affinity DataIC50: 10nMAssay Description:Antagonist activity against human delta opioid receptor expressed in CHO cells assessed as inhibition of SNC80-stimulated [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50194275(MCL-451 | H-Dmt-Tic-beta-Ala-OH | CHEMBL384915)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed