BDBM50175511 CHEMBL95051::MDL-28163::[1-(4-Fluoro-benzyl)-1H-benzoimidazol-2-yl]-{1-[2-(4-methoxy-phenyl)-ethyl]-piperidin-4-yl}-methanone

SMILES COc1ccc(CCN2CCC(CC2)C(=O)c2nc3ccccc3n2Cc2ccc(F)cc2)cc1

InChI Key InChIKey=DIPBPGRFGZKMEF-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50175511   

TargetSubstance-P receptor(Guinea pig)
TBA

Curated by ChEMBL
LigandPNGBDBM50175511(MDL-28163 | [1-(4-Fluoro-benzyl)-1H-benzoimidazol-...)
Affinity DataIC50: 5.30nMAssay Description:Antagonistic activity against Tachykinin receptor 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175511(MDL-28163 | [1-(4-Fluoro-benzyl)-1H-benzoimidazol-...)
Affinity DataIC50: 7.20nMAssay Description:Antagonistic activity against histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2010
Entry Details Article

TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175511(MDL-28163 | [1-(4-Fluoro-benzyl)-1H-benzoimidazol-...)
Affinity DataIC50: 59nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175511(MDL-28163 | [1-(4-Fluoro-benzyl)-1H-benzoimidazol-...)
Affinity DataIC50: 59nMAssay Description:Antagonism of the human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSubstance-K receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175511(MDL-28163 | [1-(4-Fluoro-benzyl)-1H-benzoimidazol-...)
Affinity DataIC50: 3.39E+3nMAssay Description:Compound was evaluated for the antagonistic activity against Tachykinin receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175511(MDL-28163 | [1-(4-Fluoro-benzyl)-1H-benzoimidazol-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Compound was evaluated for the antagonistic activity against NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/27/2012
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50175511(MDL-28163 | [1-(4-Fluoro-benzyl)-1H-benzoimidazol-...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibitory concentration against neurokinin NK1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed