BDBM50547124 CHEMBL242708::NCI-0001009

SMILES OCc1cc(=O)c(O)c(o1)C(Nc1ccccc1)c1ccccc1

InChI Key InChIKey=SDUJCHJWBKZEPC-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50547124   

TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547124(NCI-0001009 | CHEMBL242708)
Affinity DataIC50: 70nMAssay Description:Binding affinity to nonacylated N-terminal His6-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547124(NCI-0001009 | CHEMBL242708)
Affinity DataIC50: 200nMAssay Description:Inhibition of FITC-labeled palmitate tracer binding to N-terminal His6-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21-Co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547124(NCI-0001009 | CHEMBL242708)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CPM binding to N-terminal His6-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cells p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-5(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547124(NCI-0001009 | CHEMBL242708)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CPM binding to N-terminal His6-tagged human TEAD3 (216 to 434 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-RIPL cells p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-4(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547124(NCI-0001009 | CHEMBL242708)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CPM binding to nonacylated N-terminal His6-tagged human TEAD2 (217 to 447 residues) expressed in Escherichia coli BL21-CodonPlus (DE3)-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547124(NCI-0001009 | CHEMBL242708)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CPM binding to nonacylated N-terminal His6/GST-tagged human TEAD1 (209 to 426 residues) expressed in Escherichia coli BL21-CodonPlus (D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-3(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50547124(NCI-0001009 | CHEMBL242708)
Affinity DataKi:  2.60E+3nMAssay Description:Reversible inhibition of CPM binding to nonacylated N-terminal His6-tagged human TEAD4 (217 to 434 residues) expressed in Escherichia coli BL21-Codon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2022
Entry Details Article
PubMed