BDBM50513993 CHEMBL1630221::NITD008

SMILES Nc1ncnc2n(ccc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@]1(O)C#C

InChI Key InChIKey=NKRAIOQPSBRMOV-NRMKKVEVSA-N

Data  1 Kd  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50513993   

TargetGenome polyprotein(Zika virus)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus GZ01/2016 infected in African green monkey Vero cells assessed as antiviral activity measure...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus GZ01/2016 infected in African green monkey Vero cells assessed as antiviral activity by meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataKd:  3.43E+3nMAssay Description:Binding affinity to N-terminal His-tagged recombinant ZIKV ZG-01 RdRp (272 to 903 residues) expressed in Escherichia coli rosetta by surface plasmon ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGenome polyprotein(Zika virus)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus FSS13025/2010 infected in African green monkey Vero cells assessed as antiviral activity mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Zika virus)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50513993(CHEMBL1630221 | NITD008)
Affinity DataEC50:  137nMAssay Description:Inhibition of RNA-dependent RNA polymerase in Zika virus FSS13025/2010 infected in African green monkey Vero cells assessed as antiviral activity by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed