BDBM318447 NSC332396::US9624235, Compound 5

SMILES Cc1cc(N/N=C/c2c(C)[nH]n(-c3ccccc3)c2=O)c2cc3c(cc2n1)OCO3

InChI Key InChIKey=NVUNMXBZMBSWRJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 318447   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Pittsburgh

US Patent
LigandChemical structure of BindingDB Monomer ID 318447BDBM318447(NSC332396 | US9624235, Compound 5)
Affinity DataKi:  680nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Pittsburgh

US Patent
LigandChemical structure of BindingDB Monomer ID 318447BDBM318447(NSC332396 | US9624235, Compound 5)
Affinity DataIC50: 3.44E+4nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent