BDBM50590322 PELCITOCLAX::Pelcitoclax

SMILES CC(C)n1c(C)c(c(c1-c1ccc(Cl)cc1)-c1cc(F)cc(c1)N1CCN(CC1)c1ccc(NS(=O)(=O)c2ccc(N[C@H](CCN3CCC(CC3)C(=O)OCCCP(O)(O)=O)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)cc1)S(C)(=O)=O

InChI Key InChIKey=QIOCQCYXBYUYLH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50590322   

TargetApoptosis regulator Bcl-2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590322(Pelcitoclax | PELCITOCLAX)
Affinity DataKi: <1nMAssay Description:Binding affinity to Bcl-2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590322(Pelcitoclax | PELCITOCLAX)
Affinity DataKi: <1nMAssay Description:Binding affinity to Bcl-xL (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed